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Diabetic renal failure, also known as diabetic nephropathy, is a type of kidney disease that results from long-term diabetes. High blood sugar (glucose) levels can damage the blood vessels and tissues in the kidneys over time, leading to impaired kidney function. This condition is one of the most common complications of both type 1 and type 2 diabetes. Key points about diabetic renal failure: Causes: High blood sugar causes damage to the small blood vessels (capillaries) in the kidneys, impairing their ability to filter waste products effectively. Stages: Early stages: In the initial phases, kidney damage may not cause noticeable symptoms. There may be mild changes in kidney function and the presence of protein in the urine (albuminuria), which can be detected with urine tests. Advanced stages: As the disease progresses, kidney function deteriorates, leading to more severe symptoms such as swelling in the legs, feet, or ankles (edema), high blood pressure, and possibly even end-stage renal disease (ESRD), where the kidneys are no longer able to function, requiring dialysis or a kidney transplant. Symptoms: Protein in the urine Swelling in legs, ankles, or feet High blood pressure Fatigue Loss of appetite Nausea or vomiting Difficulty concentrating Diagnosis: Kidney function can be assessed through: Urine tests to detect albumin (a protein that leaks into urine when kidneys are damaged). Blood tests to measure creatinine levels and estimate the glomerular filtration rate (GFR), which indicates how well the kidneys are filtering waste. Imaging tests to examine kidney structure. Management: Blood sugar control: Keeping blood sugar levels within the target range is crucial in preventing or slowing the progression of diabetic nephropathy. Blood pressure management: Medications like ACE inhibitors or angiotensin receptor blockers (ARBs) may be prescribed to help control blood pressure and protect kidney function. Dietary changes: Limiting sodium intake, protein consumption, and controlling fluids to help manage kidney health. Medication: In some cases, medications like diuretics, statins, or phosphate binders may be necessary. Prevention: The best approach to preventing diabetic nephropathy involves maintaining tight control over blood glucose levels, managing high blood pressure, and adopting a healthy lifestyle with regular monitoring by healthcare professionals. Advanced stages and dialysis: If diabetic nephropathy progresses to end-stage renal disease (ESRD), kidney dialysis or a kidney transplant may be needed to maintain life. If you have diabetes, it's important to regularly check kidney function and make necessary lifestyle adjustments to minimize damage. Would you like more detailed information about treatment or preventive strategies?